↑
Select a hotspot on the figure to explore the long-term physical consequences of snakebite.
1. Head & Neurological Damage
Venom can cause direct and indirect damage to the head and nervous system. This includes permanent blindness from spitting cobras or intracranial bleeding. A devastating and unusual effect of Russell’s viper venom is its ability to destroy the pituitary gland, leading to the delayed onset of hypopituitarism (endocrine failure), requiring complex and expensive lifelong hormone replacement therapy.
2. Cardiovascular Damage
Venom toxins can directly damage the heart muscle (myocarditis) or cause severe bleeding into the pericardial sac surrounding the heart. Survivors may be at increased long-term risk of heart failure, arrhythmias, and other cardiovascular complications, though this area remains under-researched.
3. Abdominal Organ Failure
Several venoms are toxic to internal organs. Widespread muscle breakdown (rhabdomyolysis) can overwhelm the kidneys, leading to Acute Kidney Injury (AKI) and potentially irreversible Chronic Kidney Disease (CKD). Certain viper venoms can also induce acute pancreatitis, a painful inflammation that can lead to chronic conditions or diabetes.
4. Blood & Autoimmune Disorders
Venom-induced consumption coagulopathy (VICC) is a catastrophic failure of the blood clotting system. While an acute emergency, the massive inflammatory response triggered by envenoming can sometimes lead to long-term autoimmune phenomena, where the body’s immune system attacks its own tissues, causing a range of poorly understood chronic conditions.
5. Limbs & Tissue Necrosis
Cytotoxic venoms destroy skin, muscle, and bone, leading to massive tissue death (necrosis). To save a life, this often requires amputation of a limb. Survivors who keep their limbs are often left with severe scarring and contractures that freeze joints, rendering them useless. For every death, there are approximately three amputations.